Fibre Bragg Grating sensors are sensitive to temperature variations and can be used as fibre termometers. You would need to keep the fibre portion containing the grating as much fix as possible, with a good thermo-contact with the mouse skin (using specific gels).

Ciao

There are a number of thermometry systems possible to measure skin and deep tissue temperatures in high AC magnetic fields. Thermocouple systems have been described in teh literature that are filtered sufficiently to obtain artifact free temperature readings in high fields, but it is better to use fiberoptic systems with no metal in field. This minimizes perturbation of the EM field, thermal smearing errors due to thermal conduction along metal wires in high thermal gradients, as well as electromagnetic interference artifacts. There are a number of companies that make fiberoptic thermometry probes for medical applications:

1) LumaSense (http://www.lumasenseinc.com/EN/products/fluoroptic-temperature-sensors/)

2) Fiso (http://www.fiso.com/section.php?p=20)

3) Ipitek (http://www.ipitek.com/iproducts/fiber-optic-temperature-sensors)

Others

Best Industries and Alpha Omega and others make small diameter thin wall catheters to insert fiberoptic sensors into tissue. BUt for small animals like mice, you probably want to minimze probe size to minimize perturbation of measurement, and thus can poke the skin with a needle to allow introduction of bare fiberoptic sensor into the soft tissue. Fiso makes fiberoptic sensors as small as 0.21mm OD.

Thanks for your perfect information and your attention to my question. I agree with you. but one problem that I have with optical fiber is their high costs. Would you please guild me to a cheaper solution?

I will suggest the use of small diameter optical fibre (SDOF) as we once developed a novel method for measuring light intensity at different temperature. This can measure up to 180 degree celcius. This probably allay the fear of high costs you raised as the diameter of SDOF ranges between 12-20 microns.

I think FBG sensors are the best choice. They are small, have good metrological properties (e.g., short response time, good accuracy and sensibility, and a measurement range which fulfils your requirement). FBG sensors are not expensive (10-30 USD) but the device used to record their output (Optical Spectrum analyzer) is expensive (to buy oneOSA with very high performances you can pay much more than  10000 USD )    

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