Can anyone tel me whether can I embed mAb (herceptin) into DNA nanostructure? Since being a drug, I am confused whether it can be attached to DNA as a targeting agent?
encapsulation/embedding your mAb might compromise its activity as the reactive sites would be reduced.
though i have not worked with DNA nanostructures, i think you can chemically attach the two as they both are chemicals in crude sense and would undergo conjugation reaction under appropriate conditions and catalysts.