When dealing with isolated conditions or common condition with rare presentation, case reports are practically helpful than any other studies.individual case reports will lead us to precision medicine.
Yes, Monika Pathania , I agree; if the case report covers a relatively rare condition / rare presentation. It may be possible to find other cases also reported singly; this then enables the reader to compare / contrast. But if the case reports were not published, this could not take place. In this way, the scientific community are enabling a larger picture to be shown.
This is relevant:
Buckley, O., & Torreggiani, W. C. (2007). The demise of the case report. American Journal of Roentgenology, 189(2), W54-W55.
The full text is available, but when I entered it into RG it continued to give the below RG link despite clicking 'undo'!
It is the first paper listed here:
https://scholar.google.co.uk/scholar?q=The+demise+of+the+case+report&hl=en&as_sdt=0%2C5&as_ylo=2007&as_yhi=2007
Article The Demise of the Case Report
These are papers by ResearchGate members around this topic:
Nakamura, T., Igarashi, H., Ito, T., & Jensen, R. T. (2014). Important of case-reports/series, in rare diseases: using neuroendocrine tumors as an example. World Journal of Clinical Cases: WJCC, 2(11), 608.
Article Important of case-reports/series, in rare diseases: Using ne...
Gagne, J. J., Thompson, L., O’Keefe, K., & Kesselheim, A. S. (2014). Innovative research methods for studying treatments for rare diseases: methodological review. Bmj, 349, g6802.
Article Innovative research methods for studying treatments for rare...
The medical integration of scientific methodology and clinical reasoning, e.g. case reports, concerning the hierarchy of evidence, would require a redefinition of best practices. Medicine is mostly a practical discipline by apprenticeship and lacks scientific methodology. The advancement of clinical reasoning in medical education and practice could help to close this methodical and scientific gap.
Mary C R Wilson thanks a lot for informative articles related to this. they are of great help.
Stephen I. Ternyik you rightly pointed out, scientific methodology and CLINICAL REASONING ,is the most important . clinical reasoning is strengthened as one matures as a clinician .
Case studies are valuable tools and provide valuable insight. If they are replicated under various conditions, together they will merit even higher importance and help connect the dots leading to a well established methodology.
@ Srini Vasan u are right.
i feel usually researchers are reluctant and give less value to case reports as they are lower in hierachy of evidence . This needs to be rethought..
The point you bring in reagrd to the rare diseases is valid. We still face disorders or rare presentation in which the only evidnce we can dccount for is a case report. The capcacity to cobine them in case series is not easy retrspectivly , but one should encourage publications of theses and journals should be more acceptingf of well written case reports in the situations you mentioed.
The bias of anecdotal medicine may be present in these situations, yet its may be the best we have in the absnce of any alterantive.
This is only valid if you referíng to rare or excepcional clínica cases, indeed
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