The following are the reasons for why the High Fat diet does not increases the cholesterol-
- Marked reduction in cholesterol absorption - the mechanism for this effect is not known
- Greatly increased synthesis of bile acids - the patient synthesized roughly twice the mass of bile acids as control subjects
- Reduced endogenous cholestrol synthesis (Kern F: Normal plasma cholesterol in an 88-year-old who eats 25 eggs a day. New Eng J Med 324:986, 1991.).
An increase in the amount of cholesterol ingested each day increases the plasma concentration slightly. However, when cholesterol is ingested, the rising concentration of cholesterol inhibits the most essential enzyme for endogenous synthesis of cholesterol, thus providing an intrinsic feedback control system to prevent an excessive increase. As a result the plasma conc. usually not altered more than ±15 percent by altering the amount of cholesterol in the diet, although the response of individuals differs markedly. A high saturated fat diet increases blood cholesterol conc. 15 to 25 %. Ingestion of diet containing highly unsaturated fatty acids usually depresses the blood cholesterol conc. a slight to moderate amount (Guyton’s physiology).
The study conducted by R B Nair et al, revealed that even after 3 hour of consumption of oil/ghee, lipid profile was not increased, instead there was a decrease in lipid levels after 6 days of Snehana therapy.
Vasant et.al, (Jamnagar, 2006) in their study on standardization of Snehana observed that in group A, triglyceride & VLDL levels were increased significantly after Virecana may be due to Avara Śuddhi. In group B, triglyceride & VLDL levels were increased significantly after Snehana but after Virecana, both have came to normal level, due to the proper Śodhana. So from these evidences, it can be concluded that, after proper Snehana, one has to do proper Śodhana, otherwise lipid levels may be raised and in case of known subjects of obesity & hyperlipidemia, one should have to perform Rukshaṇa Karma before Snehana to avoid the increase of lipids.
Even though the above data shows the safety of use of Snehana therapy, one has to do multi-centered trials on large number of patients with scientific research methodology. Then only myth about Snehana can be cleared from the modern fat conscious world.
https://www.researchgate.net/publication/224898586_Effect_of_Snehapana_Internal_Oleation_On_Lipids_A_Critical_Review
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