Hello,

I would like to observe changes in gene expression in response to treatment with certain compounds taking into account effects of metabolites. I therefore need a liver model for this. Which cell line would be better suited, C3A or HepG2? The only real difference I see between them is that C3A cells don't grow when confluent, and can grow in glucose-free media. Based on this, I could go for either cell line, unless I am missing something?

Thank you in advance

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