Thanks for the additional information. Well, I guess the simple answer is: Noone is relly sure, if HepG2 was derived from HCC or HB. The original patent from 1980 states HepG2 was "derived from the liver tissue of a 15-year-old white male with a well-differentiated hepatocellular carcinoma." I found Article Hep G2 is a hepatoblastoma-derived cell line
pretty usefull to get some background information .