Have scientists been able to discover any antibiotic for MRSA bacteria until now ?
Dear Emad
as Syed told you there are many antibiotic able to treat MRSA and the problem in my opinion are the new resistances in fact S.aures already show the ability to develope resistance also against the new antibiotic generation
some examples:
Vancomicyn is also commonly used form several years for treatment of MRSA (Article The use of vancomycin in the treatment of adult patients wit...
) and VRSA (vancomicyn resistance) was also detectedArticle Vancomycin Resistance in Staphylococcus aureus
Similar observation was done for mupirocin (https://aac.asm.org/content/59/6/3350) is used widely to treat skin and soft tissue infections and to eradicate nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA).
ciao
Manuele
The tradition therapy of MRSA includes Vancomycin, Teicoplanin, Daptomycin, Linzolid, Tigecycline, rifampicin, fusidic acid, FQ.
New drug includes ceftaroline(5th cepha) and telavancin, (lipoglycopeptides) that inhibit cell wall synthesis and disrupt cell membrane permeability.
There are more information about MRSA treatment on UpToDate and be sure to check the AST result and the part of the infection because of different PK/PD of these antibiotics(e.g. Blood, Skin and soft tissue, pneumonia etc.) might cause different outcome.
We have a lot of "classical" MRSA antibiotics without increase of resistance rates (Ambrosch A., Int. Wound J 8, 567, 2011). Newer antibiotic classes are not necessesary for the MRSA problem which already decreses world wide. We should have a focus on gram-negatives
Many antibiotics can use to treat MRSA.
Some antibiotics available in oral formulations are treatment options for MRSA:
First-line therapy: trimethoprim-sulfamethoxazole (TMP-SMX; Bactrim DS, Septra DS. ...Second-line therapy: clindamycin (Cleocin). ...Third-line therapy: tetracycline or doxycycline/minocycline (Dynacin, Minocin). ...Fourth-line therapy: linezolid.
best wishes
For wound with MRSA I use mupirosin cream.for sistemik MRSA depend the result blood culture...vancomicyn is the last choice
Yes, there are many antibiotics that can be used to treat MRSA. However we cannot just choose any of the antibiotics that is available, we need to consider a lot of factors. Upon reading this article (Article Antibiotics and bioactive natural products in treatment of m...
t ) it was discussed that the selection of empiric antibiotic therapy for the treatment of MRSA infection depends on the type of disease, local S. aureus resistance patterns, availability of the drug, side effect profile, and individual patient profile.
There are antibiotics used to treat MRSA. Vancomycin is the current antibiotic of choice for treating MRSA infection. Streptogramin antibiotics, which are derived from streptomyces pristinaespiralis, are available for the therapeutic use as combination of quinupristin and dalfopristin. Clindamycin and linezolid are also used. For further explanation of these antibiotics, here's the link: Article Antibiotics and bioactive natural products in treatment of m...
There also research that a number of IV antibiotics can effectively treat MRSA infections. This includes the first-line therapy up to the fifth-line therapy. Some of the antibiotics mentioned are vancomycin, daptomycin, linezolid, tigecyline, and quinupristin or dalfopristin. Here's the link for further explanation of the said antibiotics: Gilboy, J. (2018, December 19). Updated information on MRSA infections. Retrieved October 20, 2020, from https://www.clinicaladvisor.com/home/features/updated-information-%E2%80%A8on-mrsa-infections/
MRSA may respond to vancomycin, teicoplanin, linezolid .
This article may help.
Article Methicillin-Resistant Staphylococcus aureus (MRSA): One Heal...
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