if any of you studied the alignment and elongation of prostate cancer cells (PC3) , I would like to know if you observed an alignment preference.
Hi Kripa, I just would like to know on what type of surfaces, and whether you found a distinctive alignment behavior
PC3 cells have high metastatic potential compared to DU145 cells which have a moderate metastatic potential and to LNCaP cells which have low metastatic potential.
PC3 have low testosterone-5-alpha reductase and acidic phosphatase activity, do not express PSA (prostate-specific antigen).
Furthermore, karyotypic analysis has shown that PC3 are near-triploid, presenting 62 chromosomes. Q-band analysis showed no Y chromosome. From a morphological point of view, electron microscopy revealed that PC3 show characteristics of poorly-differentiated adenocarcinoma. They have features common to neoplastic cells of epithelial origins, such as numerous microvilli, junctional complexes, abnormal nuclei and nucleoli, abnormal mitochondria, annulate lamellae, and lipoidal bodies.
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