I am looking for an astrocyte-specific AAV-PHP to perform experiments in vivo. I know people have used AAV-PHP for neurons and other cells but I couldn't find any specific AAV-PHP which only targets astrocytes.
Surya Aryal
Thank you Nasir Mustafa . Are you aware of any publication done this way?
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Francesco Roselli
combine the PHP-eB capsid with the GFAP-minipromoter. it will be expressed in astrocytes in brain and spinal cord, somehow more than the endogenous GFAP.
if it does not work, you may try intratechal AAV9.
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Surya Aryal
Thank you, Francesco Roselli. Could you please suggest any publications using either of these methods?
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