I am wondering whether there are differences in IC50 between mouse, rat and humans for myxothiazol when assayed as purified Complex III activity. I.e. does myxothiazol work unexpectedly become better in one specifies or another? Also, are there differences in LD50 between mouse and rat? The reason I ask is that in my hands, C6 rat glioma cells seem to require around 8 times less myxothiazol for respiratory inhibition than mouse and human glioma cells.

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