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Questions related from Florian L Muller
TMZ is FDA approved for GBM in humans but its overall effectiveness is limited. In intracranial mouse xenografts of run-of-the mill GBM cell lines like U87, how well does TMZ perform? I.e. is it...
17 February 2017 1,029 5 View
Cyclophosphamide is supposed to be activated by Cytochrome P450. I've treated Huh7 and PLC liver cancer cell lines with Cytochrome P450, but there is no sensitivity whatsoever, even at 500uM....
27 January 2017 7,286 5 View
I prepared a 50 mM phosphate buffer in H2O and pH'ed it to 7. I lyophilized it and dissolve it in D2O? What is the pD? And what would be the pT (I would like a tritium water solution, ultimately).
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I have xenografted human tumor lysates that I am running western blots on. I need to determine the extent of mouse cell contamination in these lysates (I don't have slides for the tumors). I am...
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