Has anyone compared BLESS with GUIDE-seq for unbiased detection of off targets following CRISPR-Cas9 genome editing?

09 July 2015 0 2K Report

The these assays utilize methods of "tagging" DSBs in the genome followed by PCR amplification of the library of sequences and NGS. They both seem rather temperamental but I wonder who (beyond the originators) have had success with these important assays.

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