Is fluoro-jade staining possible with tissue-cleared brains?

I am hoping to stain whole mouse brain hemispheres with fluoro-jade C as a marker of degeneration. We are presently working to optimize this staining for tissue cleared with the LifeCanvas SHIELD...

10 March 2020 9,709 1 View

Antibacterial liquid inhibition assay (MIC) with LB medium?

Is it possible to determine the antibacterial minimum inhibitory concentration (MIC) using a liquid inhibition assay (MIC) with Lysogeny broth medium instead of Mueller-Hinton broth? If so, is...

09 February 2020 6,330 5 View

Does it help for a prospective graduate student to have a research proposal in hand when applying to grad school?

This coming semester, I will be teaching an undergraduate class on graduate school preparation for science majors. One of the main assignments during the class will be the assembly of a full...

17 December 2019 8,239 11 View

Looking for validated questionnaires to use with both children and parents on reporting Emotional Health/difficulties?

Hi there, I'm currently doing my MSc in Psychology of Education. I'm looking to answer the following research questions for my dissertation? a) Are there differences in self-reporting of...

13 December 2019 8,779 5 View

Can a cell membrane be overloaded with too many particles attempting to enter?

When more than one biomolecules attempt to enter into a cell membrane at once (in a large quantity) does it impede the transfection process?

23 July 2019 4,149 2 View

How to improve DNA yields using DNA extraction kits designed for soil or sediment samples?

02 November 2017 9,029 3 View

How do you respond to requests for article reprints for articles which were published in journal to which you assigned copyright?

If the publication journal 'owns' the article and the request is not for teaching/educational purposes from someone who is not a current collaborator, do such requests fall under 'fair use' or...

17 October 2017 5,325 3 View

Has anyone conducted research on child protection, self harm, sucide, etc in SE Asia, more specifically Laos if possible?

Looking for any research around child protection in Laos. GoL sensors everything so I'm looking for information that might not have been censored yet. Thank you!

16 August 2017 614 3 View

Can SPSS be used to carry out a Cox PH model with a time-varying exposure covariate that changes status more than once?

I have looked through some help documents that indicate that the time-varying covariate can be constructed for an individual that has been exposed and then unexposed, or vice-versa. I was...

26 July 2017 7,097 3 View

ANOVA versus Student's t-test_Small samples

Hi, I hesitate between two statistical tests (ANOVA and Student's t-test) to compare the means of three groups (unpaired, n

20 July 2017 6,168 6 View

Why should we choose deep learning to machine learning? Why is CNN better for image classification? Can I get Typical Answer?

What Characteristics makes CNN work better?

03 March 2021 1,458 4 View

Anyone plz suggest relevant topic for research in image processing+Deep learning.?

I have selected brain tumor images ...but now found that already lots of research done n this topic.

03 March 2021 5,774 3 View

Does the pressure(-600 mmHg) affects pH?

When I conducted the degassing experiment using decompression under anaerobic condition(and I used ferrous based chelating agent), the oxidized ferric were observerd. So, could you tell me the...

03 March 2021 4,892 5 View

What is the best way to keep an anaerobic chamber anoxic in the absence of hydrogen?

I'm a graduate student who works with an anaerobe, so I often work in an anaerobic chamber. I've been working on an assay that involves the steady-state of the quinone/ quinol pool. Anoxic...

03 March 2021 2,971 1 View

How to increase a model accuracy ?

dear community, my model is based feature extraction from non stationary signals using discrete Wavelet Transform and then using statistical features then machine learning classifiers in order to...

03 March 2021 6,994 5 View

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02 March 2021 3,060 3 View

How to normalise data on OPM package from R Studio ?

Good afternoon, I recently used OmniLog from BIOLOG for my experimentations : I tested the metabolism of different strains on 2 types of plates. I have 16 strains of 3 different groups...

02 March 2021 3,584 1 View

Where to find data on trees in tropical agroforestry?

Hi, I'm looking for data (mainly related to management: growth rate, canopy size, soil and climate preferences, etc.) about tropical trees used in tropical agroforestry. Have you ever heard about...

28 February 2021 7,356 8 View

What is the difference between L1 and L2 regularization in machine learning?

L1 and L2 regularization

28 February 2021 4,187 3 View

No title

28 February 2021 9,936 2 View