You are going to need to reword your question to be more specific and start reading the literature.

Do scientists study bacterial genomes to understand antibiotic resistance? Of course the answer is yes.

Hello Ediga Sadashiva Sreehitha

The statement is false. Genomic research is very much required to study antibiotic resistance.

Why?

An exponential growth in antimicrobial use in recent decades has exerted enormous selective pressures on bacterial populations, which has dramatically accelerated the evolution of antimicrobial resistance. As soon as man develops a new class of small molecules to kill bacteria, organisms evolve to resist their action, leading to an increasing prevalence of multi-drug resistant.

The detection of antimicrobial resistance has been traditionally reliant on culture-based antimicrobial susceptibility testing. Whilst phenotyping provides direct visual evidence of how a bacterium will interact with an antimicrobial, it generally provides little or no data regarding the resistance mechanisms.

Genome research when used in this area will help to understand antibiotic resistance at the genetic level. If new antibiotic resistance loci are discovered, these databases can be immediately scanned to understand how long these genes have been circulating and how they may have entered the clinical setting. The genomes can be sequenced creating a data source that can be used to survey the evolution of pathogens.

Best.

Ediga Sadashiva Sreehitha

Genomic research has nothing to do with antibiotic resistance. Answer: It's false. Bacterial DNA modifications are the cause of antibiotic resistance. These modifications enable bacteria to adapt and resist the antibiotics intended to kill them.

I agree with the opinions of colleagues, the study of the genome had a great role, not only in understanding the mechanisms that bacteria take for resistance through their acquisition of resistance genes through the mechanisms of genetic transfer (conjugation, transformation, or transduction), or through mutations in the DNA that enables them to express resistance, but also these studies helped to understand how to develop antibiotics to be effective against pathogens. There are many of these studies that indicated this, the following links are examples of them:

Article Exploiting genomics to mitigate the public health impact of ...

Article Genome-Based Prediction of Bacterial Antibiotic Resistance

https://www.pnas.org/doi/10.1073/pnas.2016886118

https://www.phgfoundation.org/blog/the-power-of-genomics-to-tackle-the-threat-of-antibiotic-resistance

https://www.sciencedirect.com/topics/engineering/antibiotic-resistance-genes

From another point of view, there may be some truth to this statement, as the increase and exacerbation of the phenomenon of resistance to antibiotics is linked to bad practices in terms of the abuse and misuse of antibiotics in the fields of human and veterinary medicine, which causes selective pressure on these microorganisms and as a result of their attempt to survive, it develops resistance against these antibiotics by acquiring resistance genes through genetic transfer mechanisms, especially from environmental microorganisms as they are excellent sources of antimicrobial resistance genes (“environmental resistomes”), or through genetic mutations that qualify them for that...So the solution may be to rationalize the consumption of these antibiotics and reduce these bad practices that paid to exacerbate this phenomenon, as the bacteria is a living organism and it will certainly try to find a way to survive...My sincere gratitude to all.