I have a graphene-based material with secondary amine groups and carboxyl groups. I deposited antibodies in buffer solution onto the graphene and let sit at 4 C for 48 hr. Would the antibodies covalently bind to the graphene?
If course if you have the aforementioned functional groups, there will be formation of an amide from the reaction between acid-amine groups. My Regards
Dear Inna Novodchuk, first you should consider whether these antibodies will stay permanently on the surface or delibirated (or delivered), if the second option is you choice than think about a disifide conjugation bond. The way you did favors the first option. My Regards
Dear Abdelkader BOUAZIZ, thank you for your reply. I would like the antibodies to attach to the graphene permanently. Would they covalently bind to the graphene described above?
If course if you have the aforementioned functional groups, there will be formation of an amide from the reaction between acid-amine groups. My Regards
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