Hello, can anyone point me to some papers detailing how exactly exosomes end up being loaded with cargo (i,e. proteins, RNAs, carbohydrates, etc)?
Review on targeting proteins to exosomes can be found here:
http://www.biochemsoctrans.org/content/41/1/277.long
In addition, some other exosome- or vesicle-related articles,
also on intra-cellular vesicle transport.
https://www.eurekalert.org/pub_releases/2017-01/uop-prd012317.php
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001604
https://www.eurekalert.org/pub_releases/2013-03/uomm-rte032713.php
http://www.nature.com/ncb/journal/v18/n2/full/ncb3288.html
https://www.eurekalert.org/pub_releases/2002-09/hhmi-srd091802.php
https://www.ncbi.nlm.nih.gov/pubmed/16845386
https://www.eurekalert.org/pub_releases/2017-08/uok-ctr081017.php
https://www.researchgate.net/profile/Maria_Sousa9/publication/283455568_Tumour_exosome_integrins_determine_organotropic_metastasis/links/5643c0dc08aef646e6c78806/Tumour-exosome-integrins-determine-organotropic-metastasis.pdf
https://www.eurekalert.org/pub_releases/2010-09/rup-ero090910.php
http://www.genengnews.com/gen-news-highlights/studies-find-melanoma-exosomes-educate-bone-marrow-derived-cells-to-promote-metastasis/81246817
https://www.eurekalert.org/pub_releases/2014-10/uotm-ce102314.php
http://news.ku.edu/new-lab-chip-could-revolutionize-early-diagnosis-cancers-using-exosomes
https://medicalxpress.com/news/2014-10-cancer-exosome-micro-factories-aid.html
http://www.nature.com/news/cancer-cells-can-infect-normal-neighbours-1.16212
Regards,
Joachim
Article Tumour exosome integrins determine organotropic metastasis
Maybe this paper can shed a light.
CELL ADHESION & MIGRATION
2017, VOL. 11, NO. 2, 127–134
http://dx.doi.org/10.1080/19336918.2016.1251000
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