Endometriosis can cause infertility through different mechanisms : 1. Pelvic, tubal and uterine adhesions. 2. endometrial tissues secreted toxic substances which negatively affect spermatoza and decrease their fertilizing ability. 3. Vaginisimus, vaginal nodules or mass. 4. Ovulatory dysfunction in 10% of cases.
Endometriosis is a disease in which visible lesions may b just a tip of ice berg ...a laproscopy suggestive of minimal grade 1 endpmetriosis may b cause of infertility ...deep dysprunia .are some symptoms of endometriosis which may b cause of infertility ...also it is pertinent to mention that visible or non visiblr lesions may lead to tubal adhesions ..making tubesanatony distorted functionally even though by tests tubes may b seen as patent
endometriosis cause infertility through different mechanisms:
affect ovarian function by luteolysis , lutinised unruptured follicle, oocyte maturation defect or unovulation.
tubal function: by impairing fimbrial motility, mechanical obstruction.
coital function: deep dyspareunia.
sperm function: antibodies against the sperms, macrophage phagocytosis.
early pregnancy failure: immune induced, PG induced, luteal phase insufeciency.
it can cause sub-fertility by affecting the Fallopian tubes motility and tubal blockages
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