. Does the pain for the survival of the human have any meaning?

. The cellular and tissue thermal or chemical lesion causes a sensation and avoidance reflex, to avoid further damage to the affected site

. The perception of cellular or tissue damage, by making the noxious stimulus conscious, induces, in a targeted manner, protective behaviors and limiting the damage.

. The Central Nervous System (CNS) and Peripheral System, puts us in contact through our senses, with the internal biochemical and neurophysiological environment, in addition to experiencing the external or natural environment, through sensations and reflex acts, such as perceptions and behaviors to preserve the integrity of the organism.

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