What is "monoclonal" in monoclonal antibody?

Hi, This may be a silly question, but what is monoclonal in monoclonal antibody? I am new to the field of antibody. Let say, if we generate mAb with mouse, does monoclonal mean that it is...

09 October 2018 8,951 4 View

What do peak width from gating and diffusion mean?

In mass spectrometry, people keep talking about peak width from gating and diffusion.. what do they mean?

09 October 2018 2,890 0 View

What is a difference between laboratory frame energy vs center of mass frame energy?

Hi all, Could someone explain the difference between laboratory frame energy vs center of mass frame energy?

09 October 2018 2,762 0 View

Why is laboratory frame energy always higher than the center of mass frame energy during collisions?

Hi all, Why is laboratory frame energy always higher than the center of mass frame energy during collisions? Could you explain it in terms of physics rather than mathematics?

09 October 2018 8,361 0 View

What is gas-phase basicity of acetate anion (how to compare gas-phase basicity of acetate and histidine?)?

Hi, I am trying to compare the gas-phase basicity of acetate vs histidine. Finding the gas phase basicity of histidine was fairly straightforward as it is shown on NIST chemistry webbook....

08 September 2018 3,367 3 View

How can high res MS compromise the sensitivity?

How could high resolution MS compromise the sensitivity (particularly for qTOF instrument)?

08 September 2018 7,650 2 View

What are coefficient of determinations that can be used for both linear and nonlinear fitting?

Hi all, I have a data set that I want to fit a curve. In order to determine which function agrees with my data. I need the coefficient of determination that can indicate how well it fits. But...

07 August 2017 9,688 1 View

Why are insulin and alcohol dehydrogenase used as a client protein in chaperone assay?

Hi all, I have encountered many papers that almost exclusively use insulin, alcohol dehydrogenase and beta-lactalbumin as aggregated client proteins in chaperone assays. Is there a reason why...

04 May 2017 633 1 View

What is really the n value in ITC?

04 May 2017 5,358 7 View

What type of proteins are hard to crystallize?

Hi all, I am not a crystal structural biologist. I have few questions that could be rather technical. I am aware that there are some proteins that are difficult to study using x-ray...

03 April 2017 2,729 11 View

Physics: Why do we describe light by referring to its wavelength, but microwaves and radar pulses by referring to their frequency?

In physics, the description of the properties of light generally refers to its wavelength (nm), while in the range of microwaves and radio waves we refer to the frequency of a signal (e.g. kHz or...

03 March 2021 1,682 3 View

Is there any effect of different colours of light (white, red, yellow, blue etc.) on the rate of photosynthesis? If yes, why?

Light is inevitable for the process of photosynthesis reaction. Naturally sunlight plays the vital role for this process. Light may be of different colours like white, red, yellow, blue etc....

02 March 2021 7,890 2 View

In an eye with Tyndall, does each dot correspond to an individual cell?

When you observe the presence of Tyndall in an inflamed eye: Does each of the small floating dots correspond to an individual cell or to an aggregate of cells? Does a conventional slit lamp have...

27 February 2021 6,326 2 View

Sample size determination for non-parametric tests?

How do I run a a priori sample size determination for non-parametric tests, like the Mann-Whitney U-test and the Kruskall-Wallis or other non-parametric tests that accord with the unpaired t-test...

24 February 2021 166 6 View

How can I obtain time series data by country on night-time light (brightness) ?

Hi everyone, Please, how can I obtain time series data by country on night-time light (brightness) ? I've tried, but so far all I can find are maps. I am looking for numerical data, especially in...

24 February 2021 8,625 4 View

What are difference between laser diodes, simple light emitting diodes and power light emitting diodes when operated in the visible spectrum ?

I want to illuminate a scene (small space) using LED to capture photographs or videos of some tiny objects inside the space. But am not sure if I should use a Laser LED, or simple LED or power...

22 February 2021 4,240 4 View

How to interpret this FTIR spectrum of pyrolyzed hydrochar?

20 February 2021 2,840 3 View

What is the significance of (isolated) high titers of IgG anti GD1a antibodies in an older patient with polyneuropathy?

Remote history of Campylobacter infection with reactive arthritis, and Spitz nevus (UMP). Arthropod exposure in Zika/ChikV endemic area prior to emergence of length dependent, sensory PN with...

18 February 2021 8,719 1 View

No title

The regenerated cellulose film was prepared by zinc chloride/H2O system. The zinc chloride had been washed away in the regeneration process, and the wet film which was not dried had uniform...

18 February 2021 9,538 1 View

How do I plot Pressure against crank angle degree in Fluent?

18 February 2021 8,390 3 View