17 Questions 8 Answers 0 Followers
Questions related from Nav Hh
Hi all, Why is laboratory frame energy always higher than the center of mass frame energy during collisions? Could you explain it in terms of physics rather than mathematics?
10 October 2018 8,432 0 View
Hi all, Could someone explain the difference between laboratory frame energy vs center of mass frame energy?
10 October 2018 2,828 0 View
Hi, This may be a silly question, but what is monoclonal in monoclonal antibody? I am new to the field of antibody. Let say, if we generate mAb with mouse, does monoclonal mean that it is...
10 October 2018 9,041 4 View
In mass spectrometry, people keep talking about peak width from gating and diffusion.. what do they mean?
10 October 2018 2,960 0 View
Hi, For mAb, the light chain contains the highly variable region which is responsible for binding to the antigen. Are these regions different for even the same subclass? For example, the...
10 October 2018 5,932 0 View
Hi, I am trying to compare the gas-phase basicity of acetate vs histidine. Finding the gas phase basicity of histidine was fairly straightforward as it is shown on NIST chemistry webbook....
09 September 2018 3,431 3 View
How could high resolution MS compromise the sensitivity (particularly for qTOF instrument)?
09 September 2018 7,762 2 View
Hi all, I have a data set that I want to fit a curve. In order to determine which function agrees with my data. I need the coefficient of determination that can indicate how well it fits. But...
08 August 2017 9,772 1 View
Hi all, I have encountered many papers that almost exclusively use insulin, alcohol dehydrogenase and beta-lactalbumin as aggregated client proteins in chaperone assays. Is there a reason why...
05 May 2017 699 1 View
Hi all, The n value in ITC is known to be the "binding stoichiometry". But what really is n value ? How is it defined that it is known to represent the binding stoichiometry? Thanks, Cece
05 May 2017 5,529 7 View
Hi all, I am not a crystal structural biologist. I have few questions that could be rather technical. I am aware that there are some proteins that are difficult to study using x-ray...
04 April 2017 2,824 11 View
Hi all! I am not an inorganic chemist so this might be a very simple question for inorganic chemists. I wanted to qualitatively compare electrical conductivity of transition metal ions in water...
04 April 2017 1,762 3 View
Hi all, I am learning a lot of things about the computational biology for the first time. I was curious, with the current technology, what is the possible simulation time range for a research in...
01 January 2017 3,345 5 View
Hi all, This might sound really basic. But I wanted to get more intuitive/conceptual understanding of the equation in the attached file. 1) is delt G _bind,solv the free energy required for the...
01 January 2017 7,610 0 View
Hi all, I am new to the molecular dynamics simulation for biomolecules and wanted to asked some questions. Q1. what are some fundamental differences between AMBER, GROMACS, CHARMM and AMOEBA in...
12 December 2016 9,547 2 View
Hi all, My name is Seoyeon. I am preparing metal binding experiment to a protein of interest. It was previously shown that zinc binds to the protein. For some reason I can't tell that the metal...
07 July 2016 3,489 2 View
Hi all, Can the sequence of protein change during purification? (e.g substitution) What could be the reasons? It probably depends on the type of purification used. For the context, the...
01 January 1970 4,863 3 View
