When Sodium dodecyl sulphate is used to disrupt the cell membrane to extract the the genomic DNA , doesn't the SDS used in the experiment damage the DNA that has to be extracted ?
Not expected because protein is denatured through disruption in ionic bonds present in protein. SDS has negative charge and DNA it self has negative charge, so less chance to damage in DNA.
Sodium Dodecyl Sulfate, Molecular Biology Grade (SDS), is a detergent that is known to denature proteins. It is used in denaturing polyacrylamide gel electrophoresis for the determination of protein molecular weight.