Does pulse methylprednisolon cause severe sinus bradycardia?

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Majda Khoury

In adults and in children:

Rapid administration of large doses of methylprednisolone may cause sudden death, cardiac arrhythmias, circulatory collapse and cardiac arrest .

Bradycardia can occur unrelated to the speed or duration of infusion.

http://medind.nic.in/icb/t08/i10/icbt08i10p1057.pdf

Faiq Isho Gorial

Thanks a lot Majda for your answer.Best regards

Magdy Eisa Saafan

In my institute, to give this large dose of methyl prednosolone , patient must be hospitalized under strict monitoring , to be able to early deal with complications of circulatiry failure , arrythmias especially sinus bradycardia.

Thanks a lot Magdy