Can you provide me with publications where it is shown that loss of lysine methylation of histone moiety promotes acetylation of the same moiety?
MLL4 requires acetylated h4 marks for methylation.
There is a regulatory switch between h3k9 and h3s10, however thus is not based on acetylation but phosphorylation.
Loss of h3k9 marks may be an inviting signal for HATs to acetylate the chromatin.
Hope this helps
Thanks. The last point was what I was looking for. But, I cannot find any suitable article to study. CAn you provide me some where it is worked upon as: "Loss of h3k9 marks may be an inviting signal for HATs to acetylate the chromatin."
Thank you in advance yet again.
H3 Lysine 4 Is Acetylated at Active Gene Promoters and Is Regulated by H3 Lysine 4 Methylation
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1001354
A good general information paper of global chromatin marks and dynamics
I have been trying to electroporate SKOV3 cells with a large plasmid (11kb) without much success. Any tips?
29 July 2024 3,229 1 View
I am trying to coating metal oxide into steel substrate, for better sticking planning to utilse epoxy based, Could you please suggest suitable curing agent for the coating purpose
25 July 2024 438 3 View
I am experiencing this for the Bi2Se3 sputtering target. Initially, even if the target was 2:3 in Bi : Se, with a few sputtering runs, due to the high escaping tendency of selenium, the top layer...
23 July 2024 1,649 1 View
I have been trying to extract genome from NCBI using their dataset tool, however some examples seem not to work : ./datasets download genome taxon "Homo Sapiens" --annotated --assembly-level...
20 July 2024 1,339 2 View
I want to know the best methods to automate my job and live without working?
12 July 2024 5,993 2 View
I would like know what are the best ways to earn more money as a researcher?
11 July 2024 4,695 2 View
I would like to know how do I monitor my CCTV camera at my home in Bangalore from my current location which is California in USA?
11 July 2024 831 0 View
I would like to know how to check if a given research work is human made or AI generated?
11 July 2024 8,645 5 View
I am interested in knowing how does an AI detection tool work and what's the main logic behind it? How it is able to detect the presence of AI work?
11 July 2024 3,889 6 View
I would like to know how to prove my research work is new and not copied from other people's work or AI tool?
09 July 2024 8,235 2 View
In my molecule there is Chloro group at 2-position of phenyl ring, but in 2D image it appears as methyl showing no interaction.
28 July 2024 734 0 View
through genetic modification or metabolic engineering? Is it helpful, good for health ?
22 July 2024 7,811 4 View
I am conducting free radical polymerization using Kraft lignin and MMA, with DMSO serving as the solvent and there is also an initiator. Following the reaction, I obtain a solution, but I am...
15 July 2024 9,827 1 View
I measured the fatty acids in the fish, using the internal standard method in the national standard method, I first extracted the fish oil with cable extraction, please ask me how many grams of...
02 July 2024 900 1 View
If they can be acetylated and methylated what will be the effect?
02 July 2024 4,030 2 View
To prepare polymethyl methacrylate polymer for the study of acoustic properties, a mixture of methyl methacrylate monomer and benzoyl peroxide is used. This mixture is then heated and placed on a...
27 June 2024 2,087 1 View
What surface modification procedures can be employed to enhance the interfacial bonding between the resin matrix and filler particles in dental composites?
12 June 2024 9,363 1 View
How can someone remove different artefacts leading to false results due to electrostatic and flexoelectric effects during PFM measurements? during measurement what steps can be taken to nullify...
02 June 2024 8,242 0 View
Cytosine methylation, histone acetylation, etc. represent distinct epigenetic mechanisms of gene regulation. Which example is most likely to account for transgenerational effects, such as...
31 May 2024 4,613 3 View
Hi, I was wondering if anyone using the TWIST NGS Methylation protocol has experienced issues with under-conversion of CpGs? Thanks.
29 May 2024 4,763 0 View