What are the potential metabolic markers for monitoring conditions of growing culture cell lines?

I like to know the possible markers of metabolism in cancer cells such as in monitoring glycolytic, extracellular acidification and oxygen consumption rates, effected by treatment with an extract.

08 September 2019 1,527 1 View

What best method could be used to screen protein expression profile in a cancer cell line upon novel drug testing?

I am studying gene expression profile through analyses of proteins expressed upon treatment of cancer stem cell line with a novel herbal substance (in the extract) to predict gene function in...

07 August 2019 5,634 7 View

Unbearable article publication charges is the main reason for proliferative number of publications in the predatory journals. Yes or No?. Reasons?

There are many factors to think about as possible reasons that give rise to proliferative number of publications in predatory journals. Arguably, article publication charges has been pointed as...

06 July 2019 833 24 View

What should you do when your journal send you a huge payment list after publication, that was not pre-informed before submission?

I want to know people's opinions and how to handle a case of one's journal that had already published their article, indexed it in popular databases, but as a result of their changing publisher...

05 June 2019 6,811 3 View

Is Impact Factor (IF) truly the best metric index in judging the quality of a journal?

So many metrics are currently in-use by various journals to show the quality of their journals. Again, the seemingly most mentioned metric s, Impact Factor (IF) is largely criticized as biased and...

04 May 2019 8,222 15 View

What best advice could you offer a group of authors whose article has been accepted and issue-listed but not published for more than 7 months?

How do you advise a group of authors whose papers already accepted but only listed for several months under ahead-of-print without publication as necessary?

04 May 2019 3,104 6 View

What's the meaning of each of the following terms- Cited Half-Life, Immediacy Index, Eigenfactor, Article Influence used by RG for journal ratings?

These terms (Cited half-life, Immediacy Index, Eigenfactor, Article Influence) are used by Researchgate to measure the impact of any article uploaded on their system. They are also used to rate...

03 April 2019 2,144 3 View

What is the difference between these two acronyms, ESCI and SCIE indexes in considering better journal publisher?

v Which of these two indexes really has affiliation with ISI, between Science Citation Index Expanded (SCIE) and Emerging Sources Citation Index (ESCI)? v And what does each of them stand for? v...

06 July 2018 7,195 1 View

How and where do you get ethical approval in this case scenerio?

You observe some dietary habits in humans living in your vicinity and willing to find out if this will be causal for suspected deficiencies in some blood biomarkers. Fine, they are willing to...

03 April 2018 1,304 0 View

Standard deviation (SD) or standard error of mean (SEM): which way to go; what are the factors to consider in reporting?

Which one under- or overestimates significance in the test of association?. Often times, I come across both choices in the selection of SD and SEM as a measure of spread, however, little is...

01 February 2018 4,122 2 View

How optimize the Size Exclusion Chromatography?

Hello! I'll do a size exclusion chromatography, but I only have an open column, and I'll perform the peptide extraction from yeast, using buffer lysis (sodium phosphate 50 mM/NaCl 30 mM/DNAse and...

01 March 2021 2,215 2 View

No title

01 March 2021 3,905 5 View

What test should I use to compare two or three means, if data is not normally distributed but sample size is > 30 in each group?

I personally feel this as a most confusing question. As per my understanding, if sample size is > 30, and sample is skewed, we can still use paramteric approach, as it will follow Z...

01 March 2021 1,587 6 View

Is it necessary to report effect size (ES) in statistics of biomedical research given that we already report p values routinely?

Pls share your thoughts

01 March 2021 7,330 4 View

Why there are two peaks while using the mie plot of Silver nanoparticle?

Hi, I am trying to learn the theoretical modelling of silver nanoparticle using the Mie scattering theory. After that, I discovered a software named Mieplot developed by Philip Laven, where it...

25 February 2021 7,493 6 View

How to calculate Z (the number of molecules in a unit cell) for calculating theoretical density?

I am trying to calculate the theoretical density of my ceramics materials. I use the formula below to calculate the theoretical density: Theoretical density = (Molecular weight x No. of molecules...

24 February 2021 3,823 2 View

How to handle studies which report perfect effect sizes in a meta-analysis using Pearson's r?

I'm in the process of updating a meta-analysis and in one of the new studies, effect sizes are reported as Tau-U. Two of the effect sizes are reported as Tau-U = 1.00. I am using Andy Field's...

24 February 2021 2,265 3 View

Sample size determination for non-parametric tests?

How do I run a a priori sample size determination for non-parametric tests, like the Mann-Whitney U-test and the Kruskall-Wallis or other non-parametric tests that accord with the unpaired t-test...

24 February 2021 166 6 View

How to determine a priori sample size for t-test with unequal means?

I need to conduct a a priori sample size determinations for t-test with unequal means, but I don't know the sizes of the groups nor the ratio of both groups... Can I do a sample size determination...

24 February 2021 8,289 3 View

What are alternatives to factor analysis for a small sample?

My sample size is too small to conduct a factor analysis. I created my own psychometric scale for measuring Effectiveness of Support, which contains 38 items (4 sub-scales) Im really struggling...

23 February 2021 9,287 12 View