When doing work up with celite (like for reactions with NaH, PDC), upon giving it a subsequest washing with an organic solvent like ethyl acetate, does it come in the filterate.
Use a sintered glass frit if available or even a glass funnel with a plug of cotton wool.
If you must use a Buchner funnel with filter paper, then use two filter papers and be sure to moisten them so they form an effective seal around the edges of the funnel. Using a larger filter paper and trimming it for a snug fit may also help. A small layer of sand on top of the wetted filter paper before applying celite may also help.
Buchner funnels and filter papers are fiddly. Add solvents/slurries gently as not to disturb the filter paper, try not to let the filtration run dry.
Celite is a silicaceous mixture of diatoms and does not form colloids in a similar fashion to silica.
Personally I have never had problems with celite interacting with MeOH/water/acid/base, finding it to be an ideal filtrating agent.
Like Dr. Harris said, it shouldn't unless the filter is porous.
Another thought- If the workup solution is basic (>pH 8) and polar (aqueous or >30% methanol, for example), the celite may dissolve and precipitate in an organic solvent such as ethyl acetate.
So, How to seperate it from the final product, I have tried filteration using Whatman filter paper, but I can still see appreciable celite in product.
Use a sintered glass frit if available or even a glass funnel with a plug of cotton wool.
If you must use a Buchner funnel with filter paper, then use two filter papers and be sure to moisten them so they form an effective seal around the edges of the funnel. Using a larger filter paper and trimming it for a snug fit may also help. A small layer of sand on top of the wetted filter paper before applying celite may also help.
Buchner funnels and filter papers are fiddly. Add solvents/slurries gently as not to disturb the filter paper, try not to let the filtration run dry.
Celite is a silicaceous mixture of diatoms and does not form colloids in a similar fashion to silica.
Personally I have never had problems with celite interacting with MeOH/water/acid/base, finding it to be an ideal filtrating agent.
how do we identify the celite? Is there any spectral analytical technquies are available?
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