Eric B. J. Harris

3 Questions 191 Answers 0 Followers

Questions related from Eric B. J. Harris

Why are o-iodonitrobenzene and o-fluoronitrobenzene both active in the following reaction, but the bromo and chloro derivatives are not?

Carrying out a nucleophilic aromatic substitution reaction with a carbon nucleophile, the iodo and fluoro nitrobenzenes were both active. Proceeding through the characteristic Meisenheimer...

09 September 2015 5,039 15 View

What is the most polar solvent usable in silica gel chromatography?

If you have a compound that is stubbornly stuck at the top of a column, what is the most polar eluting solvent you can use to flush it off that doesn't result in silica being carried through as a...

02 February 2015 6,094 31 View

Can anyone offer me a reasonable mechanism for the following reaction?

In attempting to form a lithiated dianion then C-alkylate with prenyl bromide an unusual product was observed in up to 50% yield which I cannot mechanistically account for. The structure was...

02 February 2015 1,369 22 View