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Questions related from Ramit Singla
Estrogen receptor alpha is distributed on the plasma membrane, cytoplasm and nucleus. I want to know the differential content of Estrogen receptor alpha in T47D cell lines.
07 July 2017 516 1 View
I have done the flash column chromatography of the crude mixture. After the slow elution at 4% Ethyl acetate in petroleum ether, the polar impurity is separated and there is not signal of the...
07 July 2017 5,524 3 View
We have performed the anti-proliferation assay and nuclear receptor binding assay and got an IC50 value for the target compounds. I am planning to perform an RT-PCR experiment for analyzing the...
06 June 2017 6,876 2 View
I am doing Ph.D. in Pharmaceutical Sciences and belong to general category. I have 2-year research experience post M.Pharm. Can someone suggest me the fellowship program from Indian Govt. I know...
02 February 2016 8,708 1 View
In the attached mechanism, what can be an alternative reagent. In this reaction TBBDA (N,N,N,N-tetrabromobenzene-1,3-disulfonamide) has been used.
06 June 2015 5,594 15 View
I have separated the compound using flash chromatography and done 2D TLC chromatography for conforming there is no impurity in the separated compound, but still I am getting double the number of...
05 May 2015 2,032 14 View
i want to learn the QSAR/QPSAR from the medicinal chemistry point of view, I have gone through many books on QSAR all have a tough mathematical background and calculation which i found a bit...
04 April 2015 2,501 5 View
has any one seen a change in the abundance of C-13 during the winter and summer season, is it possible to observe relatively high abundance of C-13 in a compound during winter as compared to...
02 February 2015 6,012 5 View
Many a times we need to study the QSAR of the designed molecules/derivatives. Is there is any free software/server available for 4D/5D QSAR study with a good reliability and results are easily...
10 October 2014 7,613 6 View
Benzyl bromide and the product formed are soluble in organic phase like ethyl acetate, the excess of benzyl bromide present in the product may lead to its deterioration. How does one separate...
10 October 2014 5,263 36 View
A medical practitioner wants to publish his finding and clinical data of a particular medicinal regimen for a treatment of a disorder. what are the key requirement for the publication. As a...
08 August 2014 8,241 2 View
I have observed a 50 conformer for a protein by experimental method of NMR solution. How to choose the best conformer for simulation study?
07 July 2014 3,338 5 View
When doing work up with celite (like for reactions with NaH, PDC), upon giving it a subsequest washing with an organic solvent like ethyl acetate, does it come in the filterate.
07 July 2014 3,418 8 View
The triphenylphosphine and p-nitophenol are used in the formation of MBH reaction, and the product and these two are soluble in ethylacetate. Triphenylposphine is insoluble in water. How can I...
04 April 2014 2,025 3 View
In MD simulation we have a numerous options of membrane like POPC, DPPC; water system like TIP4P, TIP3P and boundary condition like orthorhombic.
03 March 2014 2,344 3 View
As the normal reaction of activated alkene and aldehydic at rt would take 20-30 days on using DABCO alone.
03 March 2014 3,698 3 View
