Does anyone study oncogenic splice variants and their post translational modification events under varied stimulatory environment?

04 July 2014 0 1K Report

Comparison between non oncogenic and oncogenic splice variant, in between translation modification difference could give us leading accelerator role of oncogenes to bypass membrane associated signal to reach late transcriptional events in less time?

Badges
Science topic

Similar topics
Brachyura
Cancer

More Ajay Kumar Yadav's questions See All

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Adhesion strength of coating?

How can I determine a good adhesion strength range for coatings on polymer surfaces, such as DLC on polymer substrates? Is there a specific threshold for adhesion strength (from T-peel tests)...

10 August 2024 942 3 View

Is Galaxy.org good to use for research for analyzing data and for publication?

Hello all, I wanted to know, can I use galaxy (USA, Europe or Australia) platform for analyzing the shotgun data, and can it be used for publication purpose as well? Thanks :)

06 August 2024 6,610 4 View

Polymer wear calculation?

What is the method for analytically calculating the wear and service life of polymer-polymer sliding pairs?

04 August 2024 1,078 1 View

Which will be the best software for the Hydration shell analysis with molecular dynamics?

I am using a windows system, what software I should use for hydration shell analysis with molecular dynamics?

02 August 2024 3,143 4 View

How to convert g/kg Humic acid dose to kg/ha?

I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?

02 August 2024 7,186 6 View

How to select target material for X-Ray generation?

Generally, the target material is Mo, Co, Cu, Fe, Cr, etc, so on what basis should we choose this material?

31 July 2024 5,824 0 View

Why Powder XRD is performed after cruhsing a crystal if Single Crystal XRD analysis of the same crystal has been performed already ?

What information we can get from PXRD analysis other than from SCXRD analysis of a crystal ?

30 July 2024 6,261 4 View

Why is it not common to see similar pairs in polymer sliding pairs?

If the pairs are similar, will it reduce the adhesion due to electric charges?

29 July 2024 3,185 2 View

How to use differential equations to apply hybrid production in an inventory model ?

give suggestions

22 July 2024 5,664 2 View

How many maximum words can a literature review have ?

"I am currently working on a narrative review article for my publication as an under grad about oncogenes and their expression. I have written up to 7,000 words so far, but I am not even halfway...

27 April 2024 5,562 3 View

How gene disruption by Homologous recombination plates could give false colony?

In case of plasmid transformation gene vector could be empty for false colony but how in case of gene disruption based on homologous recombination can give false colony either antibiotic cassete...

17 October 2023 9,499 0 View

What is the best samples for molecular genetic of hepatocellular carcinoma, whether it is through blood or tissue ?

Understanding the pathways and genes in HCC plays an important role in cancer prognosis there's some molecular genetic test for oncogene and gene expression

24 December 2022 2,861 2 View

Chromossomal distribution of lncRNAs - is it worth looking for?

Hello guys, I am doing a transcriptome analyses, looking specifically at lncRNAs expression. Does it make sense to analyze them according to witch chromosome they belong to? I mean, is there a...

29 October 2022 7,563 1 View

Why does the expression of P53 and Bcl2 genes increase simultaneously?

In our experiment, we are checking and comparing two synthetic chemical compounds' impact on the expression levels of apoptotic and proto-oncogenic genes including p53, Bcl-2, cMyc, hTERT, and...

03 August 2022 1,467 2 View

Is it possible to remove oncogene from chromosome?

Proto oncogene which is produce cancer is an active form of oncogene. oncogene is present in cell chromosome with no harmfull affects. But it's activeness make cancer. So if we remove the oncogene...

01 August 2022 9,400 1 View

Whether a DNA promoter methylation primer for MSP analysis could be designed on the sites without CpG islands?

Dear everyone, Recently, i am exploring the up-stream regulatory mechanism of a specific oncogene and speculate that this oncogene is pre-transcriptionally-mediated by DNA promoter...

20 December 2021 1,128 0 View

How to deal with a very viscous probe when performing immunoFISH in an eppendorf tube?

I'm using the AbNova FISH probe for YES1 oncogene amplification (Catalog number FG0035) in H1975 cells. Since cell recovery prior to teh immunoFISH is perfomed in an eppendorf tube, I wouldn't...

30 June 2021 5,307 1 View

How to determine if missense mutations are associated with proteins involved in oncogenic signaling pathways?

I have an xlsx sequencing result file that shows missense mutations. How to determine whether these mutations are associated with proteins involved in oncogenic signaling pathways? Is there any...

20 April 2020 3,075 0 View

Which oncogne to delete(CRISPR/Cas 9) from Hepatocellular Carcinoma cell?

Recently I have a group discussion about formulating a drug for Hepatocellular Carcinoma(HCC). My group agreed on using CRISPR/Cas 9 system to cure HCC, because theoretically it is more specific...

18 April 2020 6,195 0 View