Hello Gagan Das

Yes, you may make use of CRISPR/Cas9 which is a relatively new technique that can edit DNA.

A group of researchers used CRISPR/Cas9 to delete fusion oncogenes in cancer cells without affecting the normal copies of the gene in normal cells. But it is considered potentially expensive and inefficient to do it clinically because the therapy would have to be personalized to each patient. Nevertheless, this could become a promising method for possible cancer treatment. For more information you could refer to the link below.

https://sciworthy.com/what-if-we-could-cut-out-cancer-genes/

Cancer cells rely heavily on oncogenic mutations for their growth. Such cancers are termed to have an oncogenic addiction to a particular oncogene, because they mainly depend on that oncogene’s continued activity for survival.

Presently, targeted therapy for oncogenic addiction is used which involves identification of the oncogene specific to a cancer and inhibiting the activity of the protein it encodes. Most of the targeted therapies for oncogenic addiction are small-molecule inhibitors, which binds to cell protein and block its activity. The targeted therapy may be administered as a monotherapy or in combination with chemotherapy.

Thus, targeted therapy for cancers with oncogenic addiction aims to stop the mutated oncogene that fuels the tumor.

For instance, Herceptin is used to treat HER2 positive breast cancer. Imatinib mesylate is a selective Bcr-Abl kinase inhibitor, effective in the treatment of chronic myelogenous leukemia.

Best.