Pancreatic cancer is a worst type of cancer because it kills in a very short time, and there is currently no early detection method that I know where surgery can make a difference.
Unfortunately, at this point in time, close evaluation of risk factors and clinical symptoms, as well as patient history are our most reliable information to guide clinical decision for further investigation if a suspicion of pancreatic cancer exists. In my opinion, no omics profiling could tell more than - for example - a sudden loss of weight with diabetes symptoms in adulthood.