Hi, is there anyone who wants assistance with interpretation and/or classification of mutations to determine possible causality?

While doing research on genes possibly involved in a specific phenotype, you can run in to several difficulties for the interpretation and classification of mutations found, consequently making...

09 October 2017 9,968 2 View

Is there a simple way to determine if a mutation introducing a premature stopcodon signals nRNA degragdation?

11 December 2014 967 6 View

Is there a database/source for dinosaur DNA and/or protein sequences?

I want to study specific protein sequences to better understand their functional properties. I think that such information from this group of animals may help in this understanding.

06 July 2014 8,506 2 View

Would it be possuible to determine why two homologous proteins show a high degree of species specificity for the same ligand?

If two proteins are known for there distinct functions, but show affinity for the ligand of at least one other between species (bovine>human), could this be analysed?

04 May 2014 2,061 5 View

What is or are the best bioinformatic tools to assess the structural and functional implication of a non-synonymous mutations in humans?

There are several tools available to predict such implication, but the why of using one or even more remains unclear to me. Does someone have an idea of "the best" methods to be used. Moreover, is...

03 April 2014 7,441 10 View

Protein-protein interactions: are there any reliable programs to predict interaction between proteins using homology-based molecular structures?

I want to know how two proteins of interst interact with each other by using their homology-based molecular structure. I know from experimental data which part of each protein is required for...

03 April 2014 2,878 11 View

Looking for protein-protein docking software. Any suggestions and experiences?

Would like to get some assistance with simulating/estimating the interactions between two proteins to beteer understand structure-function properties.

09 October 2013 296 8 View

Where to publish your data?

If you have data on phylogenetics, functional divergence and 3d structures, where should you publish it?

09 October 2013 4,381 7 View

How to write a good grants proposal?

I want to continue my career in Academia in the field of bioinformatics.

09 October 2013 8,134 4 View

I want to be a reviewer for journals in bioinformatics and computational biology. Any options?

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09 October 2013 9,470 3 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

i have some problem with chtMultiRegionSimpleFoam

--> FOAM FATAL ERROR: Maximum number of iterations exceeded From function Foam::scalar Foam::species::thermo::T(Foam::scalar, Foam::scalar, Foam::scalar, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar) const) const [with Thermo = Foam::hConstThermo >; Type = Foam::sensibleEnthalpy; Foam::scalar = double; Foam::species::thermo = Foam::species::thermo >, Foam::sensibleEnthalpy>] in file /home/ubuntu/OpenFOAM/OpenFOAM-4.1/src/thermophysicalModels/specie/lnInclude/thermoI.H at line 66. FOAM aborting #0 Foam::error::printStack(Foam::Ostream&) at ??:? #1 Foam::error::abort() at ??:? #2 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::calculate() at ??:? #3 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::correct() at ??:? #4 ? at ??:? #5 __libc_start_main in "/lib/x86_64-linux-gnu/libc.so.6" #6 ? at ??:?

24 March 2021 0 0 View