PANCREATOGENIC DIABETES, CHRONIC PANCREATITIS, PANCREATIC CANCER and RADIO-CESIUM.

Radionuclide contamination in terrestrial ecosystems has reached a dangerous level. The major artificial radionuclide present in the environment is cesium (137-Cs and 134-Cs). In humans, animals, and plants cesium ion (Cs+) behaves like potassium ion (K+) and it is localized mainly inside the cells. Pancreas and salivary glands accumulate, secrete and eliminate Cs in the intestine and with the feces and by the kidney with the urine. Gemici et al. reported that volumetric decrease of pancreas after abdominal irradiation and that it is time to consider pancreas as an organ at risk for high radio sensibility [3]. Ingested radiocesium can cause severe pancreatitis and secondary diabetes (type 3c) , which are on the rise in the world. Venturi studied the correlation between the geographical map of these diseases and the map of nuclear plant accidents, atomic bomb testing, and radioactive fallout and reported that pancreas is able to absorb in great quantity radioactive cesium causing pancreatitis and cancer with damage of pancreatic islands with diabetes [1-2]. In fact, diabetes mellitus increased in contaminated population, particularly children and adolescents, after Chernobyl and Fukushima [4,5,6, 7] nuclear incidents. At the same time, worldwide pancreatic diseases, diabetes and environmental radiocesium are also increasing [7].

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REFERENCES

1. Venturi, Sebastiano (2020). Correlation between radioactive cesium and the increase of pancreaticcancer: A Hypothesis. Biosfera. 12 (4): 81–90. doi:10.24855/biosfera.v12i4.556. ISSN 1872-3136.

2. Venturi S. (2021). Cesium in Biology, Pancreatic Cancer, and Controversy in High and Low RadiationExposure Damage. Int. J. Environ. Res. Public Health, 18, 8934. https://doi.org/10.3390/ijerph1817893

3. Gemici, C., Yaprak, G., Ozdemir, S. et al. Volumetric decrease of pancreas after abdominalirradiation, it is time to consider pancreas as an organ at risk for radiotherapy planning. RadiatOncol 13, 238 (2018). https://doi.org/10.1186/s13014-018-1189-5

4. Zalutskaya A, et al. (2004). "Did the Chernobyl incident cause an increase in Type 1 diabetes mellitusincidence in children and adolescents?". Diabetologia; 47 (1): 147–148.doi:10.1007/s00125-003-1271-9.

5. Chung YS, et al. (2020). The incidence of diabetes among the non-diabetic residents in Kawauchivillage, Fukushima, who experienced evacuation after the 2011 Fukushima Daiichi nuclear power plantdisaster. Environ Health Prev Med. 8;25(1):13. doi: 10.1186/s12199-020-00852-x. PMID: 32384869.https://ro-journal.biomedcentral.com/articles/10.1186/s13014-018-1189-5.

6. YABLOKOV AV, NESTERENKO VB, NESTERENKO AV. (2009). Chernobyl: Consequences of the Catastrophefor People and the Environment. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. vol. 1181_file:///C:/Users/Standard/Downloads/Chernobyl_Consequences _of_the_ Catastroph.pdf

7. Venturi S.(2022). Prevention of nuclear damage caused by iodine and cesium radionuclides to thethyroid, pancreas and other organs. Juvenis scientia. 2022;8(2):5-14.DOI: 10.32415/jscientia_8_2_5-14.

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