some not understood pain syndromes seems to have a relation to theses nerve- receptors.
See quite dated paper Properties of cutaneous mechanoreceptors in the human hand - related to touch sensation https://web.stanford.edu/class/me327/readings/10-Vallbo84-HN-Cutaneous.pdf
From my clinical practice I have no doubt Ruffini receptors are related to pain syndromes CRPS. See Article Pathologic alterations of cutaneous innervation and vasculat...
Thank you very much, Chris. Good informations. I also believe that there are connections to pain syndromes. And it is much more difficult. For some surgeons it is very easy - everything they don´t understand is CRPS. There are some pain syndromes in the hand - where I think that Ruffini could be play an important role. Pain in the nailbed is very hard - there are much Ruffinis. Deep palm pain is something that I have seen sometimes which is very painful also. There are also a lot of Ruffinis.