Executing 5-factor 54 run Design of Experiment based upon Central Composite Design, Response Surface Methods and Desirability for robust parameter design . Each reading of 30 minutes combustion process is unsteady and data non-normal (for 1800 reading points per reading, sampled per second). Is averaging of data fundamentally alright; over an individual reading to generate 54-single-points for further analysis by ANOVA and fitting RSM and optimization by desirability? Or any special method for such unsteady data analysis?