We made a prodrug that should not be toxic unless the N-term protection CBZ is removed in the cytoplasm.
Do you know a reference about that ?
Thank you
Philippe
Not sure about cytoplasm of human cells, but some bacteria can deprotect it.
https://www.sciencedirect.com/science/article/abs/pii/S1381117712002238
Thank you.
I found that one already but I meant for human cells.
I just find this one:
https://patents.google.com/patent/US7696328B2/en
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