If you would like to use samples of your own artwork in a psychology experiment(also conducted by yourself), is this a potential conflict of interest?

The main intention is to avoid the hassle of copyright violation of others' artwork when using them for the experiment. But if you were to request for permission of use of others' images, would...

08 September 2019 6,938 3 View

Does targeting soluble protofibrils of amyloid beta plaques produce any effect on the insoluble sections of the plaques?

Based on the results of phase 2 trial of experimental anti-amyloid drug BAN2401, I was wondering if the positive effect of this antibody on dissolving the fibrils and reducing the cumulative...

06 July 2018 6,880 0 View

What is the outcome of combining antihistamine medications with antipsychotics and antidepressants?

What are the potential interactions between these three classes of drugs and how is their metabolism in an individual affected?

04 May 2018 3,493 4 View

What accounts for the differences between plasma and brain levels of amyloid plaques in Alzheimer's disease patients?

Is there a possible correlational relationship between the two?

03 April 2018 1,974 3 View

How is the effect of dopamine on the cerebrovascular system of the brain? Is it vasodilatory or vasoconstricting?

It seems that dopamine effect on cardiac vessels is mixed and varies with dose? Does this variation also apply similarly to cerebral vessels? Any application of this neurotransmitter in ischemic...

01 February 2018 6,180 2 View

How is the interaction between the brain and heart's magnetic fields like?

Is it possible to measure the brain and heart's magnetic fields in combination so as to study their influence on each other's strength?

01 February 2018 9,055 4 View

For cases of frequent nosebleeds that are hard to prevent, can promoting faster blood-clotting help lessen long-term blood loss?

Is it wise to administer drugs which promote blood clot when nosebleeds occur more than five times in a month due to a past surgical procedure? Is there any topical application type available so...

31 December 2017 7,979 1 View

Can environment factor(s) play a part in affecting intracranial hypertension?

For example, can the temperature of external surrounding affect the state of cerebrospinal fluid in the brain which in turn leads to intracranial hypertension?

11 December 2017 2,978 3 View

Is there any way to image cerebral vasoconstriction?

Is it possible using angiography, fMRI or PET scan?

11 December 2017 8,492 4 View

What are the causes of psychogenic nonepileptic seizures?

Is stress a major contributor?

11 December 2017 3,981 4 View

Why does blocking with my immunogenic peptide cause nuclear fluorescence in ICC?

Hi all, I am validating a polyclonal antibody raised against human ANT4, through WB and ICC. In most of my controls, the antibody shows very little off-target binding, but when I pre-incubate the...

03 March 2021 5,999 3 View

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03 March 2021 5,360 2 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Help request in CST microwave?

im working now on TPV solar cells and metamaterials and i realy need our help in CST microwave i have a tpv cell simulation and i want to extract particullarly the absorbtion of only the active...

02 March 2021 2,246 2 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How does an antibody have full intact antibody + half antibody?

Hello, I was just wondering how does a antibody have full intact antibody + half antibody? Is it because of the drug conjugation?

28 February 2021 1,577 1 View

Dapi fluorescence protocol for colon cell lines ?

28 February 2021 2,534 2 View

Does RNAiMAX transfection reagent work in serum free medium?

I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...

26 February 2021 10,041 3 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View

Unknown debris sheets observed in cell culture flasks?

Hi, We culture neural progenitor cells in T175 culture flasks coated with PLO-Laminin. We have successfully grown these cells with our protocol for months. Recently, we observed large sheets...

25 February 2021 3,443 4 View