Disruption the expression of a protein which belongs to a complex must affect other proteins expression of complex?

10 November 2022 0 731 Report

For example, would disruption the CUL4A or DDB1 or CRBN expression of the E3 ubiquitin ligase CUL4-RBX1-DDB1-CRBN (known as CRL4(CRBN)) affect other proteins expression of this complex?

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