Yang Meng

3 Questions 2 Answers 0 Followers

Questions related from Yang Meng

How to avoid the FBS (Fetal Bovine Serum) effect on hippo signaling pathway?

A study showed that FBS(Fetal Bovine Serum) was added to activate hippo target genes (Wang et al, 2019, Nucleic Acids Research). And, I found that both cell density and culture medium (contained...

26 November 2022 7,244 0 View

Disruption the expression of a protein which belongs to a complex must affect other proteins expression of complex?

For example, would disruption the CUL4A or DDB1 or CRBN expression of the E3 ubiquitin ligase CUL4-RBX1-DDB1-CRBN (known as CRL4(CRBN)) affect other proteins expression of this complex?

10 November 2022 714 0 View

Method/Protocol for PDX model in ovarian cancer ?

I am working onovarian cancer drug -resistance research , and I need a well animal-model to Improve my project depth. Thus, I plan to carry out the PDX model on my work. It would be great if...

05 November 2022 470 3 View