Mestinon depleted, about 1 in 5 MG patients claim to suffer 'brain fog.' This is excluding those on Prednisolone.
Article Neuropsychological assessment in myasthenia gravis
No, this research paper reports the results of one testing session in each patient. We do not mention testing before and afer medication. I think that your questions may refer to some other paper.
Patients report significant variations in cognition when meds due and one hour after. Might be a further line of thought. Have you seen the work on MG and olfactory deficiency?
This is a very interesting observation. I haven't known about that. However, I no longer work with MG patients, I switched to neurodegenerative research. So I'm not planning further research in the area of MG in the near future. I haven't read the paper on olfaction in MG. I think it would be good to talk to researchers that are currently more involved in MG research.
I have not tested the patients and I have no observation of any effect of mestinon on cognition. In some patients with blood-brain barrier damage you can expect some effect of mestinon on CNS function,particularly in patients with epilepsy, but ther are no data about effect on cognitive function.
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