Thank you Olivier Moquet , this is very helpful information!

Hello, some works reports seen H. capsulatum from soil samples, but yes, as a mold, in this phase it exhibits thin hyaline, septate hyphae and tuberculated macroconidia.

If you are interested I have been working with organic fertilizers and bat a chicken manure. I would share my paper with you.

Thank you for the paper Luisa. I'm looking into using PCR on my guano samples with a local university Biology department.

I sent the guano sample to a lab for PCR analysis. The results came back Absent with a comment that: "Sample contained PCR inhibitors. Dilutions were required."

Is it possible that the guano had Histoplasma capsulatum when collected from the cave back in 2013, but degraded and isn't there anymore? I freeze-dried the sample, which is supposed to keep fungus viable for several years.