Please (according to your profile) rewrite your question because it is too vague.

At first, what a kind of drug (p.e. Ibuprofen...) soluble in dichlormethan (DCM)in CTAB micelle and what a kind of cells (e.g. monolayer like HeLa cells or Cell suspension like CHO.

Please note that you have a different transport kinetik through the cytoplasm and later through the nucleus with the above cells.

JRG

My drug is a novel organic dye and I’m planning to do PDT studies on any suitable cell line. Currently I’m available with gastric cancer cell line SGC7901 and breast cancer cell line MDA-MB-231.

Thank you for the fast answer. Please read this link:

https://www.phe-culturecollections.org.uk/media/133182/mda-mb-231-cell-line-profile.pdf

Do you want to use CTAB micelles in :

MDA-MB-231 cells are grown at 37◦ C in Leibovitz’s L-15 medium supplemented with 2mM glutamine and 15% foetal bovine serum (FBS). This medium supports the growth of cells in environments without CO2 equilibration.

What a kind of drug for this cell Linie? How do you want to give the micelles/What a concentration?

Test the toxicity of your new drug (see google Scholar for dye(s) similar to your new dye).

According to the structure of your new dye, you can check the transport with the lipophilic/hydrophilic ratio).

New organic dye e.g. fluorochrome can be basic (like MB) or acid (like Eosin) or neutral ( like Pyrene) . What a kind of them?

Good luck

JRG