We regularly use both a Qubit 4 fluorometer and the TapeStation 4150 to measure DNA concentrations. We follow the recommended procedures for both devices but the TapeStation consistently gives the concentration as 2-4 times lower than the Qubit. The TapeStation concentration measures 200-5000 bp. Is this expected or should I be concerned? Does this base pair range exclude enough DNA to account for the lower concentration?

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