To conduct in vivo studies to evaluate the effectiveness of cell therapy
Saif Wahid
Genetic diversity: Outbred mice, such as ICR/CD1, have a high level of genetic diversity. This diversity helps in reducing the potential bias caused by genetic factors and makes the findings more applicable to a broader population. Reproducibility: Using outbred mice helps in improving the reproducibility of experimental results. As the genetic variation among individual mice is higher, it is easier to replicate the study findings across different experiments and laboratories. Translatability: Outbred mice are considered more representative of the general population, making the results obtained from studies using these mice more applicable to humans. This enhances the translatability of the findings from animal models to clinical settings. Availability and cost: ICR/CD1 mice are readily available and relatively inexpensive compared to other strains or genetically modified mice. This makes them a preferred choice for many research laboratories, especially when conducting large-scale in vivo studies.
Yes, it is possible to use outbred ICR/CD1 mice as laboratory animals for studying the effectiveness of mesenchymal stem cell (MSC) therapy in vivo. In fact, ICR/CD1 mice are commonly used in various research fields, including biomedical research and preclinical studies.
Here are a few reasons why outbred ICR/CD1 mice can be suitable for studying the effectiveness of MSC therapy:
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