Clavulanate inhibitor concentration?

16 June 2023 1 3K Report

What is the concentration of Clavulanate inhibitor that I should use in assay to obtain full inhibition of B-lactamase activity?

Adam B Shapiro

It will depend on which beta-lactamase enzyme you are using. Clavulanate is most potent against Ambler class A enzymes.

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