Diverse endophytic microbes construct complex interactions with their living hosts. Some are mutually supportive and others parasitic, giving a large influence to plant health..These show strong netamaticidal and antibacterial potential. Endophytic microorganisms exist within the living tissues of most plant species and do so in a variety of relationships, ranging from symbiotic to slightly pathogenic. Root endophytic microorganisms are seen as promising alternatives to replace chemical pesticides and
fertilizers in sustainable and organic agriculture systems. The capability of colonizing internal host tissues has made endophytes valuable for agriculture as a tool to improve crop performance. This association is often mutualistic: endophytes provide the plant with antagonism against diseases. its products are also used to control of plant diseases .