Can you introduce a software that can be used to compare the Kd value between nucleic acid- nucleic acid complex and nucleic acid - aptamer complex ?

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Jesper Sejrup Nielsen

I use GraphPrism, which has a number of builtin features to measure Kd and can be used to fit data to different types of curves.

Jesper

Wang Xuchu

Thanks for your timely answer, jesper.

But is there any instrument I can utilize to predict the Kd value just based on the dsDNA suquence i have designed ?