I'm planning to use a cox regression in a future study exploring time-to-event or survival analysis comparing a control with an experimental group. I've seen sample size calculated through several packages, but I prefer G*Power and wanted to know if anyone's done this. Any resources would be appreciated.
Hello Eden,
No, g*power doesn't have a direct method to estimate N for Cox regression models. However, here are some links that will get you on your way:
1. A previous RGate reply to a similar question, with links to formulae as well as a couple of online sample size calculators:
https://www.researchgate.net/post/Sample_size_calculation_for_cox_regression
2. Guidance for degree to which a target covariate is independent of any other covariates in a model, and general sample size estimation:
https://www.ijmhs.net/articles/1444805158Determining_the_Sample_Size_and_Power_for_Cox_Regression_Analysis.pdf
3. Guidance for minimum events per variable, based on a simulation study performed on a large, real data set:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045274/
Good luck with your work.
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