A stand alone HPGe detector provides U-isotope concentration via the inherent radioactivity of the isotopes. So far Jorge is right.
But in combination with an excitation source the HPGe detector provides XRF information ( e.g. U-total) as any other ED-XRF spectrometer systems. It is just a matter of appropriate calibration and data evaluation.
what if i use the x-ray fluorescence emitted from U-235 and its daughters and also for U-238 assuming secular equilibrium is attained in the two decay series is that also will give not me any results about ppm of U-235 and U-238 using EDXRF ??.
via XRF you are not able to destinguish between U-235 and U- 238 or any other U-isotpes. The sets of electron energy levels of all U-isotopes are identical. So XRF will give you the U concentration of all U-isotopes together, as Jorge already stated above (U-total).