The module of the CAD detector is corona Veo. It has been idle for a long time. And it was not well maintained before idle.
I have replaced the gas filters and flushed the system with a 50/50 mixture of water/methanol for over 48h. Despite this, the baseline remains high at round 2pA. And the noise is ahout 0.08pA with an 80/20 mixture of water/methanol at a flow rate of 1mL/min.
I have been advised that the sample flow paths, such as the nebulizer and electrodes, may need cleaning.
Could anyone provide guidance on how to clean these components?
If you have encountered similar issues while using a CAD detector, please share your experience with me.