MInimisation before docking?

I am trying to do both docking and molecular dynamics simulation. Should I minimise the protein structure after adding amino acids far from active site before docking? I have taken a PDB structure...

02 November 2020 4,798 4 View

Does anyone have reference papers for microhardness behaviour of AISI 316 L SS on HAp powder mixed EDM?

Reference papers on 1. Micro hardness behavior of AISI 316 L SS 2. Surface Topography 3. Hap Powder mixed EDM

04 January 2019 1,975 3 View

Which software is best equipped for Energy market simulator modeling?

Basically, Power World Simulator has been pretty popular for Energy Market Simulator Modeling (Educational Purpose) due to the incremental cost parameters in generator module and many more...

16 August 2018 2,646 4 View

Is it possible to feed the data output from MATLAB model or script files to ETAP simulation?

11 July 2016 9,674 3 View

Does the space of Raviart-Thomas finite elements contain the space of piecewise constant functions in triangular mesh?

Is the piecewise finite element space subset of RT space?

17 November 2015 9,173 3 View

Which equilibration buffer be used to equilibrate protein cleanup spin column of AllPrep RNA/Protein kit (Qiagen)?

They didn't supply the equilibration buffer. However I need to equilibrate the column so which buffer could be used? I am planning to do western blot.

30 September 2014 6,943 2 View

What chemical can be added to stop Fenton's reaction?

I am working on Fenton's oxidation and I would like to know if there is any chemical that will stop Fenton's oxidation without increasing the pH. I have seen NaOH being used but that increases pH....

14 March 2014 5,062 21 View

What is an easy way for isolation?

I am working on the isolation and identification of flavonoids. I have different fractions of ethyl acetate extract of a plant. I got those fractions after doing chromatography on silica gel. The...

08 January 2013 3,151 13 View

Column chromatography

I am doing chromatography of Ethyl Acetate Fraction in ods column . Initially I used 80% meoh in water . Then I decreased the polarity gradually to 90% and 100% meoh. However, some part of the...

20 December 2012 8,292 4 View

Can anyone suggest me really applicable paper describing the modeling and simulation of MVDC electric power system architecture for all-electric ship?

1. It would be better if the paper describes in detail about the modeling and simulation of all-electric ship(AES) loads (normal load as well as pulsed load). 2. What other software are usually...

01 January 1970 7,378 2 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

What is involved in morphological changes of SEM images of a substance?

In the sem analysis of CaCO3 nanaoparticles, the morphology images showed spherical shaped particles but the proposed morphology for these type of nanoparticles is trigonal. I prepared the...

01 March 2021 1,960 4 View

What are the new 2D nanomaterials were used for Silver nanoparticles stabilization?

In the stabilization of AgNPs are vital in current research interest. However, some of the 2D nano-materials like graphene oxide, MoS2, etc... previously used to stabilize it. But still they shown...

01 March 2021 2,207 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

I want to performe MALDI-TOF MS for bacterial identification, I would appreciate it if anyone can tell me the matrix solution preparation protocol ?

based on what I've studied on multiple papers, for peptide and protein identification Alpha-cyano-4-hydroxycinnamic acid (CHCA) is an appropriate matrix to use, I also know that the CHCA powder...

26 February 2021 6,799 3 View

How does charge on working electrode changes with rising potential?

During performing CV of a GCE or modified GCE, we rise the potential in the first half of the cycle and reduce it in reverse half. During the first half, what is the nature of charge on GCE or...

25 February 2021 7,994 3 View

How to increase solubility of Poly acrylic acid in Dioxane solvent?

I am working with Polyacrylic acid (100.000Da) and instead of water, I need to use another solvent (dioxane) to dissolve PAA. However, because of the high molecular weight, it's quite hard to...

25 February 2021 2,225 5 View

How to delaminate copper in water-based anodes?

Hello everyone, I'm looking for a way to delaminate copper current collector of water-based anodes in Li-ion batteries without damaging the graphite film. I tried different materials such as HNO3...

24 February 2021 3,785 3 View

Thermal reduction of graphene oxide.?

I am trying to reduce graphene oxide by thermally but I have no proper information regarding this. Can any one help me regarding the details about temperature and time for the reduction of...

23 February 2021 4,155 4 View

Can I use acetic acid with an ELITE WAX Perkin Elmer column for Gas Chromatography?

Hi! I would want to know if I can use acetic acid with an ELITE WAX Perkin Elmer column for Gas Chromatography. This column has a polyethylene glycol phase, but I can't find the manual to check...

22 February 2021 730 2 View